ATM s exist just about everywhere these days.  So don't bother with the AMex travelers cheques or feeling obligated to exchage money at the airport currency  exchange desks.

Good suggestions! I would add that you should let your credit card companies know that you'll be travelling, too. Many of them will shut down your credit line if your card is used internationally without proper advance notice. Also, if you're carrying cash in USD$, make sure it's not all in $50s or $20s. These are the most frequently counterfeited denominations & may cause you trouble if you're trying to exchange large amounts of money. Have your passport ready when you are exchanging currency -- many locations won't do it if you don't have US ID.

Happy travels!

If you want a few Euro's to have on hand prior to landing in country, then I would do some exchange before you leave. I always carry a little ($200) US Cash in case of an emergency, but primarly I just use my ATM card to withdraw EURO's when I need cash, and use my credit cards for major purchases. Don't forget, the Credit Card company will hit you with a service charge of around 3% everytime you use your card overseas. So I primarly get enought Euro and pay cash for the majority of things. You will not have a problem finding an ATM machine. Also.. avoid drawing cash advance from your Credit Card, rates are high.

Good luck.. enjoy the trip.. Italy is FANTASTIC.